Protein profile

PA1116

hypothetical protein

Genome: NC_002516.2

Gene: PA1116 Structure source: AlphaFold UniProt Q9I4L9
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Amino acids 279
Annotations 1
Features 22
PDB binders 0
Druggability 0.613

Overview

Basic information about this protein and its source genome.

Accession
PA1116
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1116
Status
annotated
Amino acids
279
Structure source
AlphaFold
GO
GO:0003676 Binding to a nucleic acid.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.613
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

22 records
Show feature table
Start End DB Term Name
73 131 Pfam PF13509 S1 domain
73 131 InterPro IPR039566 Conserved virulence factor B, S1 domain
4 66 Pfam PF13509 S1 domain
4 66 InterPro IPR039566 Conserved virulence factor B, S1 domain
1 279 PIRSF PIRSF012524 YitL_S1
1 279 InterPro IPR014464 Conserved virulence factor B
217 277 Gene3D G3DSA:1.10.10.10 -
217 277 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily
220 277 Pfam PF17783 CvfB-like winged helix domain
220 277 InterPro IPR040764 Conserved virulence factor B-like, winged helix domain
75 145 Gene3D G3DSA:2.40.50.140 -
75 145 InterPro IPR012340 Nucleic acid-binding, OB-fold
7 72 Gene3D G3DSA:2.40.50.140 -
7 72 InterPro IPR012340 Nucleic acid-binding, OB-fold
71 133 SMART SM00316 S1_6
71 133 InterPro IPR022967 RNA-binding domain, S1
146 208 SMART SM00316 S1_6
146 208 InterPro IPR022967 RNA-binding domain, S1
146 214 Gene3D G3DSA:2.40.50.140 -
146 214 InterPro IPR012340 Nucleic acid-binding, OB-fold
1 277 PANTHER PTHR37296 CONSERVED VIRULENCE FACTOR B
1 277 InterPro IPR014464 Conserved virulence factor B

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1116
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.613
2 0.439