Protein profile

PA1139

hypothetical protein

Genome: NC_002516.2

Gene: PA1139 Structure source: AlphaFold UniProt Q9I4J6

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Amino acids 282

Annotations 0

Features 15

PDB binders 0

Druggability 0.706

Overview

Basic information about this protein and its source genome.

Accession: PA1139
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA1139
Status: annotated
Amino acids: 282
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Periplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.706

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

MAIPSIPRLAVLTLGLALAAAASAADEAQLVEAINAYRGQVQSCGGQASGELPPLAADPRLALPVNAAGDLQQAMAQAAYPMVNVQSISLSGPRDAGAAMKALQESFCRVVLDPQFVDVGVSRQDRDWRIVLARPLLRGGMGDWQAEGQKLLERINAARGQARQCGGKPYAAAQPLAWNATLGGAAEAHSRAMANGNFFDHLDRDGRTPGDRAELAGYSGGLVGENIAAGQDGVDKVVDGWLASPGHCANLMNPGYRELGAAYATDPKSDAGIYWTAMFGSP

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records

Show feature table

Start	End	DB	Term	Name
152	279	Pfam	PF00188	Cysteine-rich secretory protein family
1	24	SignalP_EUK	SignalP-noTM	SignalP-noTM
20	24	Phobius	SIGNAL_PEPTIDE_C_REGION	C-terminal region of a signal peptide.
145	280	SUPERFAMILY	SSF55797	PR-1-like
145	280	InterPro	IPR035940	CAP superfamily
149	280	CDD	cd05379	CAP_bacterial
9	19	Phobius	SIGNAL_PEPTIDE_H_REGION	Hydrophobic region of a signal peptide.
149	281	PANTHER	PTHR31157	UNCHARACTERIZED
1	24	Phobius	SIGNAL_PEPTIDE	Signal peptide region
152	279	InterPro	IPR014044	CAP domain
1	8	Phobius	SIGNAL_PEPTIDE_N_REGION	N-terminal region of a signal peptide.
143	279	Gene3D	G3DSA:3.40.33.10	CAP
143	279	InterPro	IPR035940	CAP superfamily
25	282	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1	19	SignalP_GRAM_POSITIVE	SignalP-TM	SignalP-TM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1139	AlphaFold	—	—	full sequence	—	Viewing

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Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.706