Protein profile

PA1166

hypothetical protein

Genome: NC_002516.2

Gene: PA1166 Structure source: AlphaFold UniProt Q9I4H1
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Amino acids 262
Annotations 1
Features 14
PDB binders 0
Druggability 0.81

Overview

Basic information about this protein and its source genome.

Accession
PA1166
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1166
Status
annotated
Amino acids
262
Structure source
AlphaFold
GO
GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.81
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
46 258 Pfam PF01738 Dienelactone hydrolase family
46 258 InterPro IPR002925 Dienelactone hydrolase
1 18 SignalP_EUK SignalP-noTM SignalP-noTM
1 18 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
14 257 PANTHER PTHR22946 UNCHARACTERIZED
1 18 Phobius SIGNAL_PEPTIDE Signal peptide region
14 18 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
19 262 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
3 13 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
11 260 Gene3D G3DSA:3.40.50.1820 alpha/beta hydrolase
11 260 InterPro IPR029058 Alpha/Beta hydrolase fold
21 258 SUPERFAMILY SSF53474 alpha/beta-Hydrolases
21 258 InterPro IPR029058 Alpha/Beta hydrolase fold
1 2 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1166
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.81