Protein profile

PA1175

nitrate reductase biosynthesis protein NapD

Genome: NC_002516.2

Gene: PA1175 napD Structure source: AlphaFold UniProt Q9I4G2
Export view
Amino acids 109
Annotations 3
Features 9
PDB binders 0
Druggability 0.419

Overview

Basic information about this protein and its source genome.

Accession
PA1175
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1175 napD
Status
annotated
Amino acids
109
Structure source
AlphaFold
GO
GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005048 Binding to a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized. GO:0051224 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.419
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
  • GO:0005048 Binding to a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized.
  • GO:0051224 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
6 74 Gene3D G3DSA:3.30.70.920 -
1 82 PANTHER PTHR38603 CHAPERONE NAPD
1 82 InterPro IPR005623 Chaperone NapD, nitrate reductase assembly
87 109 MobiDBLite mobidb-lite consensus disorder prediction
5 74 FunFam G3DSA:3.30.70.920:FF:000004 Chaperone NapD
5 83 Hamap MF_02200 Chaperone NapD [napD].
5 83 InterPro IPR005623 Chaperone NapD, nitrate reductase assembly
6 78 Pfam PF03927 NapD protein
6 78 InterPro IPR005623 Chaperone NapD, nitrate reductase assembly

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1175
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.419
1 0.228