Protein profile

PA1189

Zn-dependent metalloprotease

Genome: NC_002516.2

Gene: PA1189 sprT Structure source: AlphaFold UniProt Q9I4E9
Export view
Amino acids 165
Annotations 3
Features 9
PDB binders 0

Overview

Basic information about this protein and its source genome.

Accession
PA1189
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1189 sprT
Status
annotated
Amino acids
165
Structure source
AlphaFold
GO
GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0008270 Binding to a zinc ion (Zn). GO:0006950 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
  • GO:0008270 Binding to a zinc ion (Zn).
  • GO:0006950 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
3 159 Hamap MF_00746 Protein SprT [sprT].
3 159 InterPro IPR023483 Uncharacterised protein family SprT
118 159 Pfam PF17283 SprT-like zinc ribbon domain
118 159 InterPro IPR035240 SprT-like, zinc ribbon domain
7 159 SMART SM00731 sprt_6
7 159 InterPro IPR006640 SprT-like
10 98 Pfam PF10263 SprT-like family
10 98 InterPro IPR006640 SprT-like
1 158 PANTHER PTHR38773 PROTEIN SPRT

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model PA1189 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1189
AlphaFold — — full sequence — Viewing