Protein profile

PA1211

hypothetical protein

Genome: NC_002516.2

Gene: PA1211 Structure source: AlphaFold UniProt Q9I4C7
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Amino acids 211
Annotations 3
Features 12
PDB binders 0
Druggability 0.942

Overview

Basic information about this protein and its source genome.

Accession
PA1211
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1211
Status
annotated
Amino acids
211
Structure source
AlphaFold
GO
GO:0004016 Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. GO:0006171 The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.942
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0004016 Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
  • GO:0016787 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
  • GO:0006171 The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
36 207 SUPERFAMILY SSF53474 alpha/beta-Hydrolases
36 207 InterPro IPR029058 Alpha/Beta hydrolase fold
13 21 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
22 211 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 21 Phobius SIGNAL_PEPTIDE Signal peptide region
4 12 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 18 SignalP_EUK SignalP-noTM SignalP-noTM
13 210 Gene3D G3DSA:3.40.50.1820 alpha/beta hydrolase
13 210 InterPro IPR029058 Alpha/Beta hydrolase fold
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
21 203 Pfam PF12697 Alpha/beta hydrolase family
21 203 InterPro IPR000073 Alpha/beta hydrolase fold-1

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1211
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.942