Overview
Basic information about this protein and its source genome.
- Accession
- PA1358
- Gene
- PA1358
- Status
- annotated
- Amino acids
- 132
- Structure source
- Experimental + AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Cytoplasmic
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 1 | 132 | PIRSF | PIRSF500687 | MTase_demethylubiq_bact |
| 1 | 132 | InterPro | IPR027259 | Predicted 3-demethylubiquinone-9 3-methyltransferase, bacterial |
| 73 | 132 | Gene3D | G3DSA:3.30.720.110 | - |
| 5 | 130 | CDD | cd06588 | PhnB_like |
| 5 | 130 | InterPro | IPR028973 | PhnB-like |
| 7 | 72 | Gene3D | G3DSA:3.30.720.100 | - |
| 3 | 130 | SUPERFAMILY | SSF54593 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| 3 | 130 | InterPro | IPR029068 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| 1 | 132 | PIRSF | PIRSF021700 | 3-demethylubiquinone_Mtase |
| 1 | 132 | InterPro | IPR009725 | Predicted 3-demethylubiquinone-9 3-methyltransferase |
| 3 | 131 | PANTHER | PTHR33990 | PROTEIN YJDN-RELATED |
| 5 | 129 | Pfam | PF06983 | 3-demethylubiquinone-9 3-methyltransferase |
| 5 | 129 | InterPro | IPR028973 | PhnB-like |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
1 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 1 | 0.904 | ||||||
| 2 | 0.209 |
Pockets (P2RANK)
Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).
| P2RANK | Sticks | Spheres | Surfaces | Score | Probability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|---|
| 1 | 2.34 | 0.06 | ||||||
| 2 | 2.08 | 0.047 | ||||||
| 3 | 1.85 | 0.036 |
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 1 | 0.905 |