Protein profile

PA1406

hypothetical protein

Genome: NC_002516.2

Gene: PA1406 Structure source: AlphaFold UniProt Q9I3T8

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Amino acids 252

Annotations 1

Features 8

PDB binders 0

Druggability 0.464

Overview

Basic information about this protein and its source genome.

Accession: PA1406
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA1406
Status: annotated
Amino acids: 252
Structure source: AlphaFold

GO:0016779 Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor).

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.464

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0016779 Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor).

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
40	118	SUPERFAMILY	SSF81301	Nucleotidyltransferase
40	118	InterPro	IPR043519	Nucleotidyltransferase superfamily
21	80	CDD	cd05403	NT_KNTase_like
40	72	Pfam	PF01909	Nucleotidyltransferase domain
40	72	InterPro	IPR002934	Polymerase, nucleotidyl transferase domain
10	74	ProSiteProfiles	PS50152	2'-5'-oligoadenylate synthase N-terminal region profile.
22	112	Gene3D	G3DSA:3.30.460.10	Beta Polymerase, domain 2
22	112	InterPro	IPR043519	Nucleotidyltransferase superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1406	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
2				0.464
3				0.239
7				0.209