Protein profile

PA1441

hypothetical protein

Genome: NC_002516.2

Gene: PA1441 Structure source: AlphaFold UniProt Q9I3Q6

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Amino acids 427

Annotations 2

Features 12

PDB binders 0

Druggability 0.765

Overview

Basic information about this protein and its source genome.

Accession: PA1441
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA1441
Status: annotated
Amino acids: 427
Structure source: AlphaFold

GO:0009424 The portion of the bacterial-type flagellum that connects the filament to the basal body. GO:0071973 Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Periplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.765

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

GO:0009424 The portion of the bacterial-type flagellum that connects the filament to the basal body.
GO:0071973 Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records

Show feature table

Start	End	DB	Term	Name
176	203	MobiDBLite	mobidb-lite	consensus disorder prediction
1	114	MobiDBLite	mobidb-lite	consensus disorder prediction
367	385	MobiDBLite	mobidb-lite	consensus disorder prediction
275	386	Gene3D	G3DSA:3.30.750.140	-
275	386	InterPro	IPR038610	FliK-like, C-terminal domain superfamily
25	43	MobiDBLite	mobidb-lite	consensus disorder prediction
17	427	PANTHER	PTHR37533	FLAGELLAR HOOK-LENGTH CONTROL PROTEIN
367	413	MobiDBLite	mobidb-lite	consensus disorder prediction
46	74	MobiDBLite	mobidb-lite	consensus disorder prediction
294	372	Pfam	PF02120	Flagellar hook-length control protein FliK
294	372	InterPro	IPR021136	Flagellar hook-length control protein-like, C-terminal
288	371	CDD	cd17470	T3SS_Flik_C

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1441	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.765
3				0.481
2				0.344