Protein profile

PA1488

hypothetical protein

Genome: NC_002516.2

Gene: PA1488 Structure source: AlphaFold UniProt Q9I3M4
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Amino acids 412
Annotations 1
Features 15
PDB binders 0
Druggability 0.708

Overview

Basic information about this protein and its source genome.

Accession
PA1488
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1488
Status
annotated
Amino acids
412
Structure source
AlphaFold
GO
GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.708
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MSITEQVDVAIVGSGPAGLAAAIELRRQGVARVCVLERDGEAGGIPRHCAHPPFGLREHGRLLTGPAYAQRNVEQAERAGVDIRLRHSVVALAAAGLLQLATPEGPRSLRATRVLLATGARETPRSARLLGGDRPLGVINTGALQAYLYLQGLKPFERPLIVGTELVSLSAVMSCRRAGIRPVAMLERNARATARWPLSLFPRLCGVPMHFSSELLEIEGRGRVEAARVRLGDGRVERIACDGILLSGRFVPESSLVRLSHLELDPASGGPRIDQFGRCSDPAYFAAGNLLRPIETAGWSFREGRRIAGLLAADLRAELPSAAPGIAIDCSGPLKLCVPQRLLADPTPGLAHLQLRVSEAASGRLRILADGRPVWERALSCLPERRLLVPLAALRLPPDTRRLEVAFLTSGH

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
9 28 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature
111 129 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature
269 291 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature
206 222 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature
8 30 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature
112 120 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature
4 406 PANTHER PTHR42949 ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT B
8 298 Gene3D G3DSA:3.50.50.60 -
8 298 InterPro IPR036188 FAD/NAD(P)-binding domain superfamily
2 315 SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain
2 315 InterPro IPR036188 FAD/NAD(P)-binding domain superfamily
125 249 Gene3D G3DSA:3.50.50.60 -
125 249 InterPro IPR036188 FAD/NAD(P)-binding domain superfamily
8 292 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase
8 292 InterPro IPR023753 FAD/NAD(P)-binding domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1488
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.708