Protein profile

PA1494

hypothetical protein

Genome: NC_002516.2

Gene: PA1494 Structure source: AlphaFold UniProt Q9I3L8
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Amino acids 551
Annotations 1
Features 18
PDB binders 0
Druggability 0.537

Overview

Basic information about this protein and its source genome.

Accession
PA1494
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1494
Status
annotated
Amino acids
551
Structure source
AlphaFold
GO
GO:0032885 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
OuterMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.537
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0032885 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.

Sequence Features

Domain/signature hits from InterPro and related databases.

18 records
Show feature table
Start End DB Term Name
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
23 551 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
34 133 Pfam PF13600 N-terminal domain of unknown function (DUF4140)
34 133 InterPro IPR025554 Domain of unknown function DUF4140
1 22 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
221 543 Pfam PF13598 Domain of unknown function (DUF4139)
221 543 InterPro IPR037291 Domain of unknown function DUF4139
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
460 551 Gene3D G3DSA:2.60.40.2960 -
16 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
152 200 Coils Coil Coil
1 22 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
30 547 NCBIfam TIGR02231 mucoidy inhibitor MuiA family protein
30 547 InterPro IPR011935 Conserved hypothetical protein CHP02231
25 549 PANTHER PTHR31005 UNCHARACTERIZED
25 549 InterPro IPR011935 Conserved hypothetical protein CHP02231
102 122 Coils Coil Coil
4 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1494
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.537
1 0.535
7 0.379
6 0.223