Protein profile

PA1510

hypothetical protein

Genome: NC_002516.2

Gene: PA1510 Structure source: Experimental + AlphaFold UniProt Q9I3K2
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Amino acids 569
Annotations 4
Features 6
PDB binders 0
Druggability 0.798

Overview

Basic information about this protein and its source genome.

Accession
PA1510
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1510
Status
annotated
Amino acids
569
Structure source
Experimental + AlphaFold
GO
GO:0044167 The lipid bilayer surrounding the host cell endoplasmic reticulum. GO:0046872 Binding to a metal ion. GO:0006914 The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation. GO:0030968 The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.798
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

4 GO

Gene Ontology (GO)

4
  • GO:0044167 The lipid bilayer surrounding the host cell endoplasmic reticulum.
  • GO:0046872 Binding to a metal ion.
  • GO:0006914 The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation.
  • GO:0030968 The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
482 503 MobiDBLite mobidb-lite consensus disorder prediction
50 340 SUPERFAMILY SSF53474 alpha/beta-Hydrolases
50 340 InterPro IPR029058 Alpha/Beta hydrolase fold
35 538 PANTHER PTHR11440 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED
187 536 Gene3D G3DSA:3.40.50.1820 alpha/beta hydrolase
187 536 InterPro IPR029058 Alpha/Beta hydrolase fold

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

2 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 4R1D
X-ray 1.75 Å A
100.0% 1-569
PDBe RCSB PDBj File
Viewing
PDB 5H7Y
X-ray 2.19 Å B
4.7% 82-108
PDBe RCSB PDBj File
Loaded
AlphaFold PA1510
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.798

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 29.07 0.929
2 4.86 0.217
3 3.09 0.104
4 2.75 0.084
5 2.58 0.074