Protein profile

PA1558

hypothetical protein

Genome: NC_002516.2

Gene: PA1558 Structure source: AlphaFold UniProt Q9I3F9

Export view

Amino acids 210

Annotations 0

Features 13

PDB binders 0

Druggability 0.651

Overview

Basic information about this protein and its source genome.

Accession: PA1558
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA1558
Status: annotated
Amino acids: 210
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: hit
Human identity (%): 31.633
Human E-value: 2.19e-07
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.651

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

MSLKWNRPAGSLSATLILAHGAGAPMDSPFMERIAELLAAQGIAVARFEFPYMAQRREDGRKRPPNPQAQLLDCWRRVHAQVRETLDGPLALGGKSMGGRMASLLADELGADALVCLGYPFYAAGKPEKPRVAHLAGLRTPTLIVQGERDALGNREAVAGYALAPTIRLHWLAAADHDLKPLKASGLTHEQHLAATAREVAGFLRGLQGH

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records

Show feature table

Start	End	DB	Term	Name
14	204	Pfam	PF20408	Alpha/beta hydrolase domain
14	204	InterPro	IPR046879	KANL3/Tex30, alpha/beta hydrolase-like domain
5	182	SUPERFAMILY	SSF53474	alpha/beta-Hydrolases
5	182	InterPro	IPR029058	Alpha/Beta hydrolase fold
1	21	Phobius	SIGNAL_PEPTIDE	Signal peptide region
18	21	Phobius	SIGNAL_PEPTIDE_C_REGION	C-terminal region of a signal peptide.
13	195	Gene3D	G3DSA:3.40.50.1820	alpha/beta hydrolase
13	195	InterPro	IPR029058	Alpha/Beta hydrolase fold
1	8	Phobius	SIGNAL_PEPTIDE_N_REGION	N-terminal region of a signal peptide.
15	206	PANTHER	PTHR13136	TESTIS DEVELOPMENT PROTEIN PRTD
15	206	InterPro	IPR026555	KAT8 regulatory NSL complex subunit 3/Testis-expressed sequence 30 protein
22	210	Phobius	NON_CYTOPLASMIC_DOMAIN	Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
9	17	Phobius	SIGNAL_PEPTIDE_H_REGION	Hydrophobic region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1558	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
2				0.651