Protein profile

PA1645

hypothetical protein

Genome: NC_002516.2

Gene: PA1645 Structure source: Experimental + AlphaFold UniProt Q9I380
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Amino acids 135
Annotations 0
Features 11
PDB binders 0
Druggability 0.902

Overview

Basic information about this protein and its source genome.

Accession
PA1645
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1645
Status
annotated
Amino acids
135
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.902
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
20 135 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
4 14 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 19 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 19 Phobius SIGNAL_PEPTIDE Signal peptide region
20 135 Gene3D G3DSA:3.90.70.190 Domain of unknown function (DUF5086)
20 135 InterPro IPR044935 Domain of unknown function DUF5086 superfamily
1 19 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
5 134 Pfam PF16985 Domain of unknown function (DUF5086)
5 134 InterPro IPR031561 Protein of unknown function DUF5086
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
15 19 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 2XU8
X-ray 1.98 Å A,B,C
85.9% 20-135
PDBe RCSB PDBj File
Viewing
AlphaFold PA1645
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.902

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.78 0.146
2 0.94 0.004