Protein profile

PA1658

hypothetical protein

Genome: NC_002516.2

Gene: PA1658 Structure source: AlphaFold UniProt Q9I367
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Amino acids 491
Annotations 1
Features 8
PDB binders 0
Druggability 0.809

Overview

Basic information about this protein and its source genome.

Accession
PA1658
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1658
Status
annotated
Amino acids
491
Structure source
AlphaFold
GO
GO:0033103 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.809
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0033103 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
3 491 PANTHER PTHR35565 CYTOPLASMIC PROTEIN-RELATED
3 491 InterPro IPR010269 Type VI secretion system TssC-like
65 364 Pfam PF05943 EvpB/VC_A0108, tail sheath N-terminal domain
65 364 InterPro IPR044031 TssC1, N-terminal
378 488 Pfam PF18945 EvpB/VC_A0108, tail sheath gpW/gp25-like domain
378 488 InterPro IPR044032 TssC1, C-terminal
17 489 NCBIfam TIGR03355 type VI secretion system contractile sheath large subunit
17 489 InterPro IPR010269 Type VI secretion system TssC-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1658
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.809
20 0.233