Protein profile

PA1659

hypothetical protein

Genome: NC_002516.2

Gene: PA1659 Structure source: AlphaFold UniProt Q9I366
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Amino acids 135
Annotations 1
Features 8
PDB binders 0
Druggability 0.562

Overview

Basic information about this protein and its source genome.

Accession
PA1659
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1659
Status
annotated
Amino acids
135
Structure source
AlphaFold
GO
GO:0033103 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.562
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0033103 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
8 128 Gene3D G3DSA:3.10.450.40 -
26 113 Pfam PF04965 Baseplate wedge protein gp25
26 113 InterPro IPR007048 IraD/Gp25-like
24 128 SUPERFAMILY SSF160719 gpW/gp25-like
8 129 FunFam G3DSA:3.10.450.40:FF:000023 Type VI secretion system protein
28 134 PANTHER PTHR38595 CYTOPLASMIC PROTEIN-RELATED
5 134 NCBIfam TIGR03357 type VI secretion system baseplate subunit TssE
5 134 InterPro IPR017737 Type VI secretion system protein TssE1-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1659
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.425