Protein profile

PA1665

hypothetical protein

Genome: NC_002516.2

Gene: PA1665 Structure source: AlphaFold UniProt Q9I360
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Amino acids 397
Annotations 2
Features 12
PDB binders 0
Druggability 0.528

Overview

Basic information about this protein and its source genome.

Accession
PA1665
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1665
Status
annotated
Amino acids
397
Structure source
AlphaFold
GO
GO:0033103 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence. GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.528
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0033103 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.
  • GO:0005515 Binding to a protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
29 101 CDD cd00060 FHA
30 96 Pfam PF00498 FHA domain
30 96 InterPro IPR000253 Forkhead-associated (FHA) domain
209 384 Pfam PF20232 C-terminal domain of Type VI secretion system FHA protein
209 384 InterPro IPR046883 Type VI secretion system, FHA domain-containing protein, C-terminal domain
3 386 NCBIfam TIGR03354 type VI secretion system-associated FHA domain protein TagH
3 386 InterPro IPR017735 Type VI secretion system, FHA domain-containing protein
7 106 Gene3D G3DSA:2.60.200.20 -
28 70 ProSiteProfiles PS50006 Forkhead-associated (FHA) domain profile.
28 70 InterPro IPR000253 Forkhead-associated (FHA) domain
19 104 SUPERFAMILY SSF49879 SMAD/FHA domain
19 104 InterPro IPR008984 SMAD/FHA domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1665
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.528
3 0.267