Target Pathogen

Overview

Basic information about this protein and its source genome.

Accession: PA1694
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA1694 pscQ
Status: annotated
Amino acids: 309
Structure source: AlphaFold

GO

GO:0071978 Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria. GO:0050918 The directed movement of a motile cell or organism towards a higher concentration of a chemical. GO:0030254 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins. GO:0009306 The controlled release of proteins from a cell.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.983

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

4 GO

Gene Ontology (GO)

4

GO:0071978 Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria.
GO:0050918 The directed movement of a motile cell or organism towards a higher concentration of a chemical.
GO:0030254 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
GO:0009306 The controlled release of proteins from a cell.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records

Show feature table

Start	End	DB	Term	Name
232	308	SUPERFAMILY	SSF101801	Surface presentation of antigens (SPOA)
232	308	InterPro	IPR036429	SpoA-like superfamily
12	305	PANTHER	PTHR30034	FLAGELLAR MOTOR SWITCH PROTEIN FLIM
236	248	PRINTS	PR01339	Type III secretion system outer membrane O protein family signature
236	248	InterPro	IPR003283	Type III secretion system outer membrane, SpaO
280	297	PRINTS	PR01339	Type III secretion system outer membrane O protein family signature
280	297	InterPro	IPR003283	Type III secretion system outer membrane, SpaO
175	185	PRINTS	PR01339	Type III secretion system outer membrane O protein family signature
175	185	InterPro	IPR003283	Type III secretion system outer membrane, SpaO
221	307	Gene3D	G3DSA:2.30.330.10	-
221	307	InterPro	IPR036429	SpoA-like superfamily
234	303	Pfam	PF01052	Type III flagellar switch regulator (C-ring) FliN C-term
234	303	InterPro	IPR001543	Flagellar motor switch protein FliN-like, C-terminal domain
40	303	NCBIfam	TIGR02551	type III secretion system cytoplasmic ring protein SctQ
40	303	InterPro	IPR013385	Type III secretion system apparatus protein YscQ/HrcQ/SpaO

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1694	AlphaFold	—	—	full sequence	—	Viewing

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Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.983
12				0.271

PA1694