Protein profile

PA1715

type III export apparatus protein

Genome: NC_002516.2

Gene: PA1715 pscB Structure source: AlphaFold UniProt Q9I320

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Amino acids 140

Annotations 1

Features 8

PDB binders 0

Druggability 0.961

Overview

Basic information about this protein and its source genome.

Accession: PA1715
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA1715 pscB
Status: annotated
Amino acids: 140
Structure source: AlphaFold

GO:0030254 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.961

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0030254 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records

Show feature table

Start	End	DB	Term	Name
3	120	Pfam	PF05932	Tir chaperone protein (CesT) family
3	120	InterPro	IPR010261	Tir chaperone protein (CesT) family
1	126	Gene3D	G3DSA:3.30.1460.10	-
2	140	NCBIfam	TIGR02513	YscB family type III secretion system chaperone
2	140	InterPro	IPR013353	Type III secretion system chaperone YscB
2	126	SUPERFAMILY	SSF69635	Type III secretory system chaperone-like
1	126	CDD	cd17027	T3SC_IA_YscB_AscB-like
1	126	FunFam	G3DSA:3.30.1460.10:FF:000003	Type III export apparatus protein

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1715	AlphaFold	—	—	full sequence	—	Viewing

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Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
4				0.961
3				0.396
2				0.311
1				0.247