Protein profile

PA1722

type III export protein PscI

Genome: NC_002516.2

Gene: pscI PA1722 Structure source: AlphaFold UniProt Q9I315

Export view

Amino acids 112

Annotations 1

Features 4

PDB binders 0

Druggability 0.604

Overview

Basic information about this protein and its source genome.

Accession: PA1722
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: pscI PA1722
Status: annotated
Amino acids: 112
Structure source: AlphaFold

GO:0030254 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.604

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0030254 The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records

Show feature table

Start	End	DB	Term	Name
26	112	Pfam	PF17001	Type III secretion basal body protein I, YscI, HrpB, PscI
26	112	InterPro	IPR012670	Type III secretion system, YscI/HrpB
74	112	NCBIfam	TIGR02497	type III secretion system inner rod subunit SctI
74	112	InterPro	IPR012670	Type III secretion system, YscI/HrpB

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1722	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
4				0.604
2				0.577
1				0.512