Protein profile

PA1753

hypothetical protein

Genome: NC_002516.2

Gene: PA1753 Structure source: AlphaFold UniProt Q9I2Y4
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Amino acids 165
Annotations 1
Features 13
PDB binders 0
Druggability 0.741

Overview

Basic information about this protein and its source genome.

Accession
PA1753
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1753
Status
annotated
Amino acids
165
Structure source
AlphaFold
GO
GO:0005524 Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.741
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MIRSILYATDLGLYAPYVLQHALSLTRAYNAELYVVHVVEPLGLFAESVLQTYLDTERLQDLRAQGLDNVMESIEKRVLEGFRDELGELPQDAALVKSVRVVQGDPPQMILDEAEKLAVDLIVAGSHSHGTQLDTPLGRTAARLVQLAEVPVYLVPMLQHRSRDL

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0005524 Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
5 155 CDD cd00293 USP_Like
134 156 PRINTS PR01438 Universal stress protein signature
134 156 InterPro IPR006015 Universal stress protein A family
2 20 PRINTS PR01438 Universal stress protein signature
2 20 InterPro IPR006015 Universal stress protein A family
116 128 PRINTS PR01438 Universal stress protein signature
116 128 InterPro IPR006015 Universal stress protein A family
1 156 SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like
1 156 Pfam PF00582 Universal stress protein family
1 156 InterPro IPR006016 UspA
1 162 Gene3D G3DSA:3.40.50.620 HUPs
1 162 InterPro IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
75 156 PANTHER PTHR46268 STRESS RESPONSE PROTEIN NHAX

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1753
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.741
2 0.607