Overview
Basic information about this protein and its source genome.
- Accession
- PA1768
- Gene
- PA1768
- Status
- annotated
- Amino acids
- 179
- Structure source
- Experimental + AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Unknown
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 1 | 22 | Phobius | SIGNAL_PEPTIDE | Signal peptide region |
| 6 | 16 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. |
| 24 | 159 | Gene3D | G3DSA:2.40.70.10 | Acid Proteases |
| 24 | 159 | InterPro | IPR021109 | Aspartic peptidase domain superfamily |
| 1 | 22 | SignalP_EUK | SignalP-noTM | SignalP-noTM |
| 23 | 179 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. |
| 1 | 5 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. |
| 17 | 22 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. |
| 1 | 22 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM |
| 27 | 165 | SUPERFAMILY | SSF50630 | Acid proteases |
| 27 | 165 | InterPro | IPR021109 | Aspartic peptidase domain superfamily |
| 3 | 173 | PANTHER | PTHR38037 | ZN_PROTEASE DOMAIN-CONTAINING PROTEIN |
| 27 | 168 | Pfam | PF05618 | Putative ATP-dependant zinc protease |
| 27 | 168 | InterPro | IPR008503 | Putative ATP-dependent zinc protease |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
1 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 1 | 0.32 | ||||||
| 2 | 0.212 |