Protein profile

PA1814

hypothetical protein

Genome: NC_002516.2

Gene: PA1814 Structure source: AlphaFold UniProt Q9I2T0
Export view
Amino acids 253
Annotations 2
Features 6
PDB binders 0
Druggability 0.892

Overview

Basic information about this protein and its source genome.

Accession
PA1814
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1814
Status
annotated
Amino acids
253
Structure source
AlphaFold
GO
GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0008757 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.892
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0008168 Catalysis of the transfer of a methyl group to an acceptor molecule.
  • GO:0008757 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
85 131 Pfam PF08241 Methyltransferase domain
85 131 InterPro IPR013216 Methyltransferase type 11
23 201 Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39
23 201 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
90 178 SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases
90 178 InterPro IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1814
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.665
5 0.295
1 0.257