Protein profile

PA1831

hypothetical protein

Genome: NC_002516.2

Gene: PA1831 Structure source: AlphaFold UniProt Q9I2R4
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Amino acids 236
Annotations 2
Features 11
PDB binders 0
Druggability 0.234

Overview

Basic information about this protein and its source genome.

Accession
PA1831
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1831
Status
annotated
Amino acids
236
Structure source
AlphaFold
GO
GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0016791 Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.234
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
  • GO:0016791 Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
3 226 PANTHER PTHR20935 PHOSPHOGLYCERATE MUTASE-RELATED
2 228 Gene3D G3DSA:3.40.50.1240 -
2 228 InterPro IPR029033 Histidine phosphatase superfamily
3 179 SMART SM00855 PGAM_5
3 179 InterPro IPR013078 Histidine phosphatase superfamily, clade-1
4 101 CDD cd07067 HP_PGM_like
4 101 InterPro IPR013078 Histidine phosphatase superfamily, clade-1
4 219 Pfam PF00300 Histidine phosphatase superfamily (branch 1)
4 219 InterPro IPR013078 Histidine phosphatase superfamily, clade-1
1 232 SUPERFAMILY SSF53254 Phosphoglycerate mutase-like
1 232 InterPro IPR029033 Histidine phosphatase superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1831
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.234