Protein profile

PA1833a

alpha/beta hydrolase

Genome: NC_002516.2

Gene: YP_008719748.1 Structure source: ColabFold
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Amino acids 291
Annotations 0
Features 12
PDB binders 0
Druggability 0.94

Overview

Basic information about this protein and its source genome.

Accession
PA1833a
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
YP_008719748.1
Status
annotated
Amino acids
291
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.94
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
1 150 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
151 170 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
151 169 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
4 273 Gene3D G3DSA:3.40.50.1820 alpha/beta hydrolase
4 273 InterPro IPR029058 Alpha/Beta hydrolase fold
27 117 Pfam PF12146 Serine aminopeptidase, S33
27 117 InterPro IPR022742 Serine aminopeptidase, S33
3 265 SUPERFAMILY SSF53474 alpha/beta-Hydrolases
3 265 InterPro IPR029058 Alpha/Beta hydrolase fold
170 291 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
2 287 PIRSF PIRSF037442 UCP037442_abhydr
2 287 InterPro IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold PA1833A
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.94