Protein profile

PA1841

hypothetical protein

Genome: NC_002516.2

Gene: PA1841 Structure source: AlphaFold UniProt Q9I2Q4

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Amino acids 165

Annotations 1

Features 10

PDB binders 0

Druggability 0.679

Overview

Basic information about this protein and its source genome.

Accession: PA1841
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA1841
Status: annotated
Amino acids: 165
Structure source: AlphaFold

GO:0002161 The hydrolysis of an incorrectly aminoacylated tRNA.

Target profile

Computed evidence for target prioritization.

Human off-target: hit
Human identity (%): 34.194
Human E-value: 9.28e-21
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.679

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

MSAKMDEQALLALLRELAIDSQRVEHPAIASIEEYYAQGIELPDQGIKNLFLRNRKGTRHYLVLLDERKEADLPGIAEQIGESRLSFASVERLREYLGVELGCVTPFALVNDPQHRVEVLLDDAIRQDQLLGFHPLVNTATECIRYADLLAFLAHTGHEPRLIRA

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0002161 The hydrolysis of an incorrectly aminoacylated tRNA.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records

Show feature table

Start	End	DB	Term	Name
5	163	SUPERFAMILY	SSF55826	YbaK/ProRS associated domain
5	163	InterPro	IPR036754	YbaK/aminoacyl-tRNA synthetase-associated domain superfamily
1	165	Gene3D	G3DSA:3.90.960.10	-
1	165	InterPro	IPR036754	YbaK/aminoacyl-tRNA synthetase-associated domain superfamily
26	152	Pfam	PF04073	Aminoacyl-tRNA editing domain
26	152	InterPro	IPR007214	YbaK/aminoacyl-tRNA synthetase-associated domain
4	163	PANTHER	PTHR31423	YBAK DOMAIN-CONTAINING PROTEIN
4	163	InterPro	IPR040285	Prolyl-tRNA editing protein ProX/PRXD1
19	163	CDD	cd04335	PrdX_deacylase
2	164	FunFam	G3DSA:3.90.960.10:FF:000005	Putative prolyl-tRNA synthetase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1841	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.679