Protein profile

PA1845

hypothetical protein

Genome: NC_002516.2

Gene: tsi1 PA1845 Structure source: Experimental + AlphaFold UniProt Q9I2Q0
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Amino acids 172
Annotations 0
Features 8
PDB binders 0
Druggability 0.281

Overview

Basic information about this protein and its source genome.

Accession
PA1845
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
tsi1 PA1845
Status
annotated
Amino acids
172
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.281
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
3 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 19 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
20 172 Gene3D G3DSA:2.40.128.650 -
20 172 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
16 19 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 19 Phobius SIGNAL_PEPTIDE Signal peptide region
1 19 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 2 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

4 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 3VPJ
X-ray 2.50 Å E,F,G,H
100.0% 1-172
PDBe RCSB PDBj File
Viewing
PDB 4EQA
X-ray 1.60 Å C,D
89.0% 20-172
PDBe RCSB PDBj File
Loaded
PDB 4FQB
X-ray 2.69 Å B,D,F,H
89.0% 20-172
PDBe RCSB PDBj File
Loaded
PDB 4FGI
X-ray 3.20 Å B,D,F,H
86.6% 24-172
PDBe RCSB PDBj File
Loaded
AlphaFold PA1845
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer