Protein profile

PA1911

sigma factor regulator FemR

Genome: NC_002516.2

Gene: femR PA1911 Structure source: AlphaFold UniProt Q9I2J3

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Amino acids 316

Annotations 0

Features 10

PDB binders 0

Druggability 0.95

Overview

Basic information about this protein and its source genome.

Accession: PA1911
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: femR PA1911
Status: annotated
Amino acids: 316
Structure source: AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Periplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.95

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records

Show feature table

Start	End	DB	Term	Name
101	235	FunFam	G3DSA:2.60.120.1440:FF:000002	Probable transmembrane sensor
4	316	PIRSF	PIRSF018266	FecR
4	316	InterPro	IPR012373	Fe(2+)-dicitrate sensor, transmembrane component
101	233	Gene3D	G3DSA:2.60.120.1440	-
12	313	PANTHER	PTHR30273	PERIPLASMIC SIGNAL SENSOR AND SIGMA FACTOR ACTIVATOR FECR-RELATED
12	313	InterPro	IPR012373	Fe(2+)-dicitrate sensor, transmembrane component
15	57	Pfam	PF16220	Domain of unknown function (DUF4880)
15	57	InterPro	IPR032623	FecR, N-terminal
114	204	Pfam	PF04773	FecR protein
114	204	InterPro	IPR006860	FecR protein

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1911	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
4				0.95