Overview
Basic information about this protein and its source genome.
- Accession
- PA1975
- Gene
- PA1975
- Status
- annotated
- Amino acids
- 387
- Structure source
- AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Cytoplasmic
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 2 | 382 | PANTHER | PTHR40252 | - |
| 239 | 364 | Pfam | PF10442 | FIST C domain |
| 239 | 364 | InterPro | IPR019494 | FIST, C-domain |
| 236 | 366 | SMART | SM01204 | FIST_C_2 |
| 236 | 366 | InterPro | IPR019494 | FIST, C-domain |
| 34 | 235 | SMART | SM00897 | FIST_2 |
| 34 | 235 | InterPro | IPR013702 | FIST domain, N-terminal |
| 37 | 233 | Pfam | PF08495 | FIST N domain |
| 37 | 233 | InterPro | IPR013702 | FIST domain, N-terminal |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
PA1975
|
AlphaFold | — | — | full sequence | — | Viewing |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 10 | 0.854 | ||||||
| 4 | 0.824 |