Protein profile

PA1981

hypothetical protein

Genome: NC_002516.2

Gene: PA1981 Structure source: AlphaFold UniProt Q9I2C6
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Amino acids 215
Annotations 0
Features 16
PDB binders 0
Druggability 0.96

Overview

Basic information about this protein and its source genome.

Accession
PA1981
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA1981
Status
annotated
Amino acids
215
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
32.955
Human E-value
4.17e-16
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Extracellular

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.96
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
31 207 PANTHER PTHR14136 UNCHARACTERIZED
1 18 Phobius SIGNAL_PEPTIDE Signal peptide region
127 166 Pfam PF00805 Pentapeptide repeats (8 copies)
127 166 InterPro IPR001646 Pentapeptide repeat
72 107 Pfam PF00805 Pentapeptide repeats (8 copies)
72 107 InterPro IPR001646 Pentapeptide repeat
167 206 Pfam PF00805 Pentapeptide repeats (8 copies)
167 206 InterPro IPR001646 Pentapeptide repeat
14 18 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 18 SignalP_EUK SignalP-noTM SignalP-noTM
115 210 Gene3D G3DSA:2.160.20.80 -
22 114 Gene3D G3DSA:2.160.20.80 -
36 209 SUPERFAMILY SSF141571 Pentapeptide repeat-like
3 13 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
19 215 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 2 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA1981
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.96
2 0.911