Protein profile

PA1985

coenzyme PQQ synthesis protein A

Genome: NC_002516.2

Gene: PA1985 pqqA Structure source: AlphaFold UniProt Q9ZAA0

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Amino acids 23

Annotations 1

Features 6

PDB binders 0

Overview

Basic information about this protein and its source genome.

Accession: PA1985
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA1985 pqqA
Status: annotated
Amino acids: 23
Structure source: AlphaFold

GO:0018189 The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): Y
Localization: Unknown

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0018189 The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records

Show feature table

Start	End	DB	Term	Name
1	19	Pfam	PF08042	PqqA family
1	19	InterPro	IPR011725	Coenzyme PQQ biosynthesis protein A
1	23	Hamap	MF_00656	Coenzyme PQQ synthesis protein A [pqqA].
1	23	InterPro	IPR011725	Coenzyme PQQ biosynthesis protein A
2	22	NCBIfam	TIGR02107	pyrroloquinoline quinone precursor peptide PqqA
2	22	InterPro	IPR011725	Coenzyme PQQ biosynthesis protein A

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

No pockets are loaded yet for the displayed AlphaFold model PA1985 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

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Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA1985	AlphaFold	—	—	full sequence	—	Viewing