Protein profile

PA2017

hypothetical protein

Genome: NC_002516.2

Gene: PA2017 Structure source: AlphaFold UniProt Q9I294
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Amino acids 309
Annotations 1
Features 14
PDB binders 0
Druggability 0.305

Overview

Basic information about this protein and its source genome.

Accession
PA2017
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2017
Status
annotated
Amino acids
309
Structure source
AlphaFold
GO
GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.305
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0005886 The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Sequence Features

Domain/signature hits from InterPro and related databases.

14 records
Show feature table
Start End DB Term Name
1 25 SignalP_EUK SignalP-noTM SignalP-noTM
50 302 Pfam PF06977 SdiA-regulated
50 302 InterPro IPR009722 SdiA-regulated
22 25 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
26 309 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 9 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
10 21 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
57 302 CDD cd09971 SdiA-regulated
57 302 InterPro IPR009722 SdiA-regulated
20 296 Gene3D G3DSA:2.120.10.30 -
20 296 InterPro IPR011042 Six-bladed beta-propeller, TolB-like
7 26 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 25 Phobius SIGNAL_PEPTIDE Signal peptide region
11 304 SUPERFAMILY SSF50956 Thermostable phytase (3-phytase)

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2017
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.305
2 0.235
6 0.226