Protein profile

PA2044

hypothetical protein

Genome: NC_002516.2

Gene: PA2044 Structure source: AlphaFold UniProt Q9I271
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Amino acids 624
Annotations 0
Features 15
PDB binders 0
Druggability 0.691

Overview

Basic information about this protein and its source genome.

Accession
PA2044
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2044
Status
annotated
Amino acids
624
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
OuterMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.691
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MPRHPFSPSFLAASVFCAATPALAALQPIAEAPLAGETEFRCQFNADNSTDCVSTYSFTILKPSGREMLSRIDRSYAETDSLIVEKAELTQPGGKPVPLDQSQIDTRTAPNPDQGFLRERQTSLAFPNLRVGTRISYTLREHFTAKPLSTQFHYILSRPPMPVRDDRFVAEFKAERPIFVRSELMDAYRIEQSADKKTLKVSLKKPQYTNYINEAGNAYLRHTPRLELGSSLDLQDNFGPFAARYNEILAAELPKGAAAAVAAVKGKPAREQVAGLMQYINDTYRYLGDWRASERGYVPFSLAEIERNGYGDCKDLAILLAAMLKAAGIKAEPTLVSRGDVVWDLLVPGMYAPNHAIVRAEVDGKTWWLDPTNPVFAPGRIMPDIQQRWALVLGADGKVRRDEIPLEAPGDTLRVTRSEHYTHDGEARVESRVELSNAPLMQLSVADRQRGRTSTDQDLCRNFAKEGSDCVLERDDSQFVLPPSYTISARLTDRRALDRLGGEYFYNRQDLASQWDAFAKYRSEGQLAELYLGEPQITSYDISLSGGKTDEPAHSCEIRSPWFDIDLQAEPAKDGGYHYRYREVQKTSWLNHDEINSAEFGKLIEQSRGCVEQLRLVVKLDKRP

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
265 334 Pfam PF01841 Transglutaminase-like superfamily
265 334 InterPro IPR002931 Transglutaminase-like
20 24 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
9 19 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 24 Phobius SIGNAL_PEPTIDE Signal peptide region
1 8 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
46 205 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857)
46 205 InterPro IPR024618 Domain of unknown function DUF3857
244 379 Gene3D G3DSA:3.10.620.30 -
25 624 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
266 420 SUPERFAMILY SSF54001 Cysteine proteinases
266 420 InterPro IPR038765 Papain-like cysteine peptidase superfamily
35 219 Gene3D G3DSA:2.60.40.3140 -
1 24 SignalP_EUK SignalP-noTM SignalP-noTM
1 24 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2044
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.691