Protein profile

PA2094

transmembrane sensor

Genome: NC_002516.2

Gene: PA2094 Structure source: AlphaFold UniProt Q9I221
Export view
Amino acids 318
Annotations 0
Features 13
PDB binders 0
Druggability 0.829

Overview

Basic information about this protein and its source genome.

Accession
PA2094
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2094
Status
annotated
Amino acids
318
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Periplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.829
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
115 205 Pfam PF04773 FecR protein
115 205 InterPro IPR006860 FecR protein
1 318 PIRSF PIRSF018266 FecR
1 318 InterPro IPR012373 Fe(2+)-dicitrate sensor, transmembrane component
84 101 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
84 101 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.
102 318 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 316 PANTHER PTHR30273 PERIPLASMIC SIGNAL SENSOR AND SIGMA FACTOR ACTIVATOR FECR-RELATED
1 316 InterPro IPR012373 Fe(2+)-dicitrate sensor, transmembrane component
1 83 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
110 233 Gene3D G3DSA:2.60.120.1440 -
12 51 Pfam PF16220 Domain of unknown function (DUF4880)
12 51 InterPro IPR032623 FecR, N-terminal

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2094
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.829
1 0.553