Protein profile

PA2102

hypothetical protein

Genome: NC_002516.2

Gene: PA2102 Structure source: AlphaFold UniProt Q9I213
Export view
Amino acids 152
Annotations 3
Features 8
PDB binders 0
Druggability 0.775

Overview

Basic information about this protein and its source genome.

Accession
PA2102
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2102
Status
annotated
Amino acids
152
Structure source
AlphaFold
GO
GO:0008235 Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0008270 Binding to a zinc ion (Zn). GO:0006508 The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.775
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0008235 Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
  • GO:0008270 Binding to a zinc ion (Zn).
  • GO:0006508 The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
5 145 Gene3D G3DSA:3.40.140.10 Cytidine Deaminase, domain 2
1 142 PANTHER PTHR34858 CYSO-CYSTEINE PEPTIDASE
4 138 ProSiteProfiles PS50249 MPN domain profile.
4 138 InterPro IPR037518 MPN domain
8 123 Pfam PF14464 Prokaryotic homologs of the JAB domain
8 123 InterPro IPR028090 JAB domain, prokaryotic
5 138 SUPERFAMILY SSF102712 JAB1/MPN domain
5 145 FunFam G3DSA:3.40.140.10:FF:000131 Sulfurylase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2102
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.775
2 0.24
3 0.222