Protein profile

PA2126

hypothetical protein

Genome: NC_002516.2

Gene: PA2126 Structure source: AlphaFold UniProt Q9I1Y9

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Amino acids 211

Annotations 1

Features 10

PDB binders 0

Druggability 0.313

Overview

Basic information about this protein and its source genome.

Accession: PA2126
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA2126
Status: annotated
Amino acids: 211
Structure source: AlphaFold

GO:0071453 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.313

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

GO:0071453 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records

Show feature table

Start	End	DB	Term	Name
53	149	Pfam	PF02195	ParB/Sulfiredoxin domain
53	149	InterPro	IPR003115	ParB/Sulfiredoxin
47	149	CDD	cd16397	IbrB_like
49	117	Gene3D	G3DSA:3.90.1530.10	-
50	183	SUPERFAMILY	SSF110849	ParB/Sulfiredoxin
50	183	InterPro	IPR036086	ParB/Sulfiredoxin superfamily
52	150	SMART	SM00470	ParB_7
52	150	InterPro	IPR003115	ParB/Sulfiredoxin
1	163	PANTHER	PTHR30083	UNCHARACTERIZED
51	120	FunFam	G3DSA:3.90.1530.10:FF:000002	Putative transcriptional regulator

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA2126	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
2				0.313