Protein profile

PA2156

hypothetical protein

Genome: NC_002516.2

Gene: PA2156 Structure source: AlphaFold UniProt Q9I1V9
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Amino acids 245
Annotations 1
Features 8
PDB binders 0
Druggability 0.356

Overview

Basic information about this protein and its source genome.

Accession
PA2156
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2156
Status
annotated
Amino acids
245
Structure source
AlphaFold
GO
GO:0003824 Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.356
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0003824 Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
26 243 PANTHER PTHR14859 CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR
5 244 Gene3D G3DSA:3.60.10.10 Endonuclease/exonuclease/phosphatase
5 244 InterPro IPR036691 Endonuclease/exonuclease/phosphatase superfamily
29 236 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family
29 236 InterPro IPR005135 Endonuclease/exonuclease/phosphatase
5 243 SUPERFAMILY SSF56219 DNase I-like
5 243 InterPro IPR036691 Endonuclease/exonuclease/phosphatase superfamily
5 245 FunFam G3DSA:3.60.10.10:FF:000020 Endonuclease/exonuclease/phosphatase family protein

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2156
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.356