Overview
Basic information about this protein and its source genome.
- Accession
- PA2157
- Gene
- PA2157
- Status
- annotated
- Amino acids
- 312
- Structure source
- AlphaFold
Target profile
Computed evidence for target prioritization.
- Human off-target
- No hit
- Gut microbiome off-target
- hit
- Essential (DEG)
- N
- Localization
- Cytoplasmic
Selected Druggability evidence
Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.
Sequence
Primary amino-acid sequence viewer.
Functional Annotations
Enzyme classification and Gene Ontology terms linked to this protein.
No GO or EC annotations are currently loaded for this protein.
Sequence Features
Domain/signature hits from InterPro and related databases.
Show feature table
| Start | End | DB | Term | Name |
|---|---|---|---|---|
| 24 | 288 | Pfam | PF01904 | Protein of unknown function DUF72 |
| 24 | 288 | InterPro | IPR002763 | Protein of unknown function DUF72 |
| 6 | 291 | SUPERFAMILY | SSF117396 | TM1631-like |
| 6 | 291 | InterPro | IPR036520 | UPF0759 superfamily |
| 1 | 292 | Gene3D | G3DSA:3.20.20.410 | Protein of unknown function UPF0759 |
| 1 | 292 | InterPro | IPR036520 | UPF0759 superfamily |
| 5 | 292 | PANTHER | PTHR30348 | UNCHARACTERIZED PROTEIN YECE |
| 5 | 292 | InterPro | IPR002763 | Protein of unknown function DUF72 |
3D Structure
Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.
Loading 3D structure...
Structural evidence
0 + 1Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.
| Entry | Method | Resolution | Chain | Coverage | Links | Status |
|---|---|---|---|---|---|---|
|
AlphaFold
PA2157
|
AlphaFold | — | — | full sequence | — | Viewing |
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer
Pockets (FPOCKET)
Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).
| FPOCKET | Sticks | Spheres | Surfaces | Druggability | Labels | Zoom | Positions |
|---|---|---|---|---|---|---|---|
| 1 | 0.417 | ||||||
| 2 | 0.308 |