Protein profile

PA2201

hypothetical protein

Genome: NC_002516.2

Gene: PA2201 Structure source: Experimental + AlphaFold UniProt Q9I1R6
Export view
Amino acids 294
Annotations 0
Features 10
PDB binders 0
Druggability 0.674

Overview

Basic information about this protein and its source genome.

Accession
PA2201
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2201
Status
annotated
Amino acids
294
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.674
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MHAFPLTLDNRLAEALPLWRNLARTDRAPRRNIDLADWKADWRELIAALDRFSRSHGYRQPFAAQGHAALENAWAWGQAAENASTLLLKAIDRGLAGAELRSIYLETAALWLDYSRLLGAARDSLREQGEVDFETAPALAPRTGQYPFALQLLAMGVLLDAQELIPALVEEVLQFDTDRLLDYLGAAALGLTSASEETFHPRPFGQLRAFFEEADGSDAQALAPYLQSQYREFFQLSPKAQKKTRRLTGPYAWGWWAMEVSALGVLYGWDDGVLRASPHYLGDLVDYARARGDA

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
177 284 Pfam PF08929 Domain of unknown function (DUF1911)
177 284 InterPro IPR015025 PoNi, C-terminal
6 129 SUPERFAMILY SSF140486 PA2201 N-terminal domain-like
6 129 InterPro IPR028997 PA2201-like, N-terminal
137 291 SUPERFAMILY SSF140731 PA2201 C-terminal domain-like
137 291 InterPro IPR028983 PA2201-like, C-terminal
1 130 Gene3D G3DSA:1.20.1440.70 -
1 130 InterPro IPR028997 PA2201-like, N-terminal
135 294 Gene3D G3DSA:1.10.3920.10 -
135 294 InterPro IPR028983 PA2201-like, C-terminal

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 2FEF
X-ray 1.90 Å A,B,C
100.0% 1-294
PDBe RCSB PDBj File
Viewing
AlphaFold PA2201
AlphaFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.674
3 0.5

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 4.86 0.217
2 1.51 0.022