Protein profile

PA2222

hypothetical protein

Genome: NC_002516.2

Gene: PA2222 Structure source: Experimental + AlphaFold UniProt Q9I1P7
Amino acids 215
Annotations 0
Features 6
PDB binders 0
Druggability 0.454

Overview

Basic information about this protein and its source genome.

Accession
PA2222
Gene
PA2222
Status
annotated
Amino acids
215
Structure source
Experimental + AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.454
Structure
Pocket

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
4 215 SUPERFAMILY SSF53955 Lysozyme-like
4 215 InterPro IPR023346 Lysozyme-like domain superfamily
1 215 Gene3D G3DSA:1.10.3690.10 -
1 215 InterPro IPR038265 PA2222-like domain superfamily
3 215 Pfam PF11508 Protein of unknown function (DUF3218)
3 215 InterPro IPR021593 Protein of unknown function DUF3218

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 2IGS
X-ray 2.17 Å A,B,C,D,E,F,G,H
100.0% 1-215
Viewing
AlphaFold PA2222
AlphaFold full sequence Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.454

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 6.22 0.311
2 1.63 0.027