Protein profile

PA2236

biofilm formation protein PslF

Genome: NC_002516.2

Gene: pslF PA2236 Structure source: AlphaFold UniProt Q9I1N3
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Amino acids 395
Annotations 3
Features 6
PDB binders 0
Druggability 0.609

Overview

Basic information about this protein and its source genome.

Accession
PA2236
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
pslF PA2236
Status
annotated
Amino acids
395
Structure source
AlphaFold
GO
GO:0016757 Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). GO:1901135 The chemical reactions and pathways involving carbohydrate derivative. GO:0044010 A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.609
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0016757 Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
  • GO:1901135 The chemical reactions and pathways involving carbohydrate derivative.
  • GO:0044010 A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
50 360 PANTHER PTHR12526 GLYCOSYLTRANSFERASE
8 389 SUPERFAMILY SSF53756 UDP-Glycosyltransferase/glycogen phosphorylase
182 366 Gene3D G3DSA:3.40.50.2000 Glycogen Phosphorylase B;
192 365 Pfam PF00534 Glycosyl transferases group 1
192 365 InterPro IPR001296 Glycosyl transferase, family 1
2 386 CDD cd03822 GT4_mannosyltransferase-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2236
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.609