Protein profile

PA2293

hypothetical protein

Genome: NC_002516.2

Gene: PA2293 Structure source: AlphaFold UniProt Q9I1I2
Export view
Amino acids 321
Annotations 1
Features 30
PDB binders 0
Druggability 0.654

Overview

Basic information about this protein and its source genome.

Accession
PA2293
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2293
Status
annotated
Amino acids
321
Structure source
AlphaFold
GO
GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.654
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016491 Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Sequence Features

Domain/signature hits from InterPro and related databases.

30 records
Show feature table
Start End DB Term Name
177 267 PANTHER PTHR12697 PBS LYASE HEAT-LIKE PROTEIN
69 310 SUPERFAMILY SSF48371 ARM repeat
69 310 InterPro IPR016024 Armadillo-type fold
2 142 Gene3D G3DSA:1.25.10.10 -
2 142 InterPro IPR011989 Armadillo-like helical
14 97 Pfam PF13646 HEAT repeats
231 315 Pfam PF13646 HEAT repeats
140 221 Pfam PF13646 HEAT repeats
143 321 Gene3D G3DSA:1.25.10.10 -
143 321 InterPro IPR011989 Armadillo-like helical
117 146 SMART SM00567 E-Z type HEAT repeats
117 146 InterPro IPR004155 PBS lyase HEAT-like repeat
55 84 SMART SM00567 E-Z type HEAT repeats
55 84 InterPro IPR004155 PBS lyase HEAT-like repeat
23 52 SMART SM00567 E-Z type HEAT repeats
23 52 InterPro IPR004155 PBS lyase HEAT-like repeat
86 115 SMART SM00567 E-Z type HEAT repeats
86 115 InterPro IPR004155 PBS lyase HEAT-like repeat
242 271 SMART SM00567 E-Z type HEAT repeats
242 271 InterPro IPR004155 PBS lyase HEAT-like repeat
148 177 SMART SM00567 E-Z type HEAT repeats
148 177 InterPro IPR004155 PBS lyase HEAT-like repeat
180 209 SMART SM00567 E-Z type HEAT repeats
180 209 InterPro IPR004155 PBS lyase HEAT-like repeat
273 302 SMART SM00567 E-Z type HEAT repeats
273 302 InterPro IPR004155 PBS lyase HEAT-like repeat
211 240 SMART SM00567 E-Z type HEAT repeats
211 240 InterPro IPR004155 PBS lyase HEAT-like repeat
198 235 ProSiteProfiles PS50077 HEAT repeat profile.
198 235 InterPro IPR021133 HEAT, type 2

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2293
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.654