Protein profile

PA2297

ferredoxin

Genome: NC_002516.2

Gene: PA2297 Structure source: AlphaFold UniProt Q9I1H8
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Amino acids 81
Annotations 3
Features 11
PDB binders 0
Druggability 0.753

Overview

Basic information about this protein and its source genome.

Accession
PA2297
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2297
Status
annotated
Amino acids
81
Structure source
AlphaFold
GO
GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0051539 Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0046872 Binding to a metal ion.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.753
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MAYRPQDIFFRSSAPVTIDEDRCIADKGCTVCVEVCPMDLLAIDPTTRKAYMAYDECWYCMPCEKDCPTGAVKVEIPYLLR

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0005737 The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
  • GO:0051539 Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
  • GO:0046872 Binding to a metal ion.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
28 71 Pfam PF13187 4Fe-4S dicluster domain
28 71 InterPro IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain
14 46 ProSiteProfiles PS51379 4Fe-4S ferredoxin-type iron-sulfur binding domain profile.
14 46 InterPro IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain
16 75 PANTHER PTHR43122 FERREDOXIN SUBUNIT OF PYRUVATE:FLAVODOXIN OXIDOREDUCTASE-RELATED
48 77 ProSiteProfiles PS51379 4Fe-4S ferredoxin-type iron-sulfur binding domain profile.
48 77 InterPro IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain
57 68 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature.
57 68 InterPro IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
15 76 Gene3D G3DSA:3.30.70.20 -
9 74 SUPERFAMILY SSF54862 4Fe-4S ferredoxins

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2297
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.753