Protein profile

PA2336

hypothetical protein

Genome: NC_002516.2

Gene: PA2336 Structure source: AlphaFold UniProt Q9I1E2
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Amino acids 446
Annotations 1
Features 12
PDB binders 0
Druggability 0.709

Overview

Basic information about this protein and its source genome.

Accession
PA2336
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2336
Status
annotated
Amino acids
446
Structure source
AlphaFold
GO
GO:0004062 Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.709
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MPRFPMLLLSAALLAAGAHAAPSVYPTGVTRYDPQKAFNQYVIFSGADRKTHLIDMNGNEVKRWDYPGFPAAVIDPALNGGKRGHVLLQLADLAAPDKLASPGNGLANQALGELDWDGKEVWRWGDQAPGGAAHQHHDQRRLANGNTLLLANKVHAVKGFAVPRVIDDVIYEVTPQGKLAWSWTASEHLDEFGFTADQLKRVRASENPDYLHINNLAPLGENRWHAAGDRRFAPDNLLLDSRNANFIAIVDKASGKVVWRLGPNLPPIDPKSARKLPRPVDQISGQHDAHLIPEGLPGAGNLLVFDNQGDAGYPSVPRGLVSGSRVLEIDPLKKQIVWQYTAEDSQQPGWAFYSAFISSARRLPNGNTLIDEGQNGRFFQVTPGGEIVWEYVSPYFGKAPRGDARSNWVYRALPVAYDWVPEGTPREEKAVNLAVPGATPQVTARR

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0004062 Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
14 445 PANTHER PTHR35340 PQQ ENZYME REPEAT PROTEIN-RELATED
1 6 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 20 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 20 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
103 378 Pfam PF05935 Arylsulfotransferase (ASST)
103 378 InterPro IPR010262 Arylsulfotransferase, bacteria
16 20 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
39 394 SUPERFAMILY SSF50998 Quinoprotein alcohol dehydrogenase-like
39 394 InterPro IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily
7 15 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 20 Phobius SIGNAL_PEPTIDE Signal peptide region
21 446 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2336
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
5 0.709
1 0.576