Protein profile

PA2362

hypothetical protein

Genome: NC_002516.2

Gene: PA2362 Structure source: AlphaFold UniProt Q9I1B7
Amino acids 252
Annotations 0
Features 11
PDB binders 0
Druggability 0.871

Overview

Basic information about this protein and its source genome.

Accession
PA2362
Gene
PA2362
Status
annotated
Amino acids
252
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.871
Structure
Pocket

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
1 209 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
233 252 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm.
210 232 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
21 233 NCBIfam TIGR03349 DotU/TssL family secretion system protein
21 233 InterPro IPR017732 Type IV / VI secretion system, DotU
12 242 PANTHER PTHR38033 MEMBRANE PROTEIN-RELATED
13 190 Gene3D G3DSA:1.25.40.590 Type IV / VI secretion system, DotU
13 190 InterPro IPR038522 Type IV / VI secretion system, DotU superfamily
72 227 Pfam PF09850 Type VI secretion system protein DotU
72 227 InterPro IPR017732 Type IV / VI secretion system, DotU
210 232 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2362
AlphaFold full sequence Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.871
4 0.784
8 0.723