Protein profile

PA2365

hypothetical protein

Genome: NC_002516.2

Gene: PA2365 Structure source: AlphaFold UniProt Q9I1B4
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Amino acids 181
Annotations 0
Features 9
PDB binders 0
Druggability 0.749

Overview

Basic information about this protein and its source genome.

Accession
PA2365
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2365
Status
annotated
Amino acids
181
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
Cytoplasmic

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.749
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

MAESTQHKLDRVRPPRVQITYDVEIGNAIEKKELPLVVGILADLSGKPDTPPAKLVERRFVDIDRDNFNEILSSISPRATLQVDNTISGDDSKLNVELRFNHIEDFDPVNLVKQVVPLRRLFEARQRLRDLLTKLDGNDDLDQLLQDVVANTEGLQEIKAARPEAEAAPAGDSEPPADQPA

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
156 181 MobiDBLite mobidb-lite consensus disorder prediction
10 160 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2
10 160 InterPro IPR008312 Type VI secretion system sheath protein TssB1
1 169 PANTHER PTHR35850 CYTOPLASMIC PROTEIN-RELATED
1 169 InterPro IPR008312 Type VI secretion system sheath protein TssB1
6 163 NCBIfam TIGR03358 type VI secretion system contractile sheath small subunit
6 163 InterPro IPR008312 Type VI secretion system sheath protein TssB1
1 175 PIRSF PIRSF028301 UCP028301
1 175 InterPro IPR008312 Type VI secretion system sheath protein TssB1

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2365
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.749
1 0.411