Protein profile

PA2366

uricase

Genome: NC_002516.2

Gene: PA2366 Structure source: AlphaFold UniProt Q9I1B3
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Amino acids 494
Annotations 0
Features 8
PDB binders 0
Druggability 0.867

Overview

Basic information about this protein and its source genome.

Accession
PA2366
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2366
Status
annotated
Amino acids
494
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
Y
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.867
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
68 368 Pfam PF05943 EvpB/VC_A0108, tail sheath N-terminal domain
68 368 InterPro IPR044031 TssC1, N-terminal
1 491 PANTHER PTHR35565 CYTOPLASMIC PROTEIN-RELATED
1 491 InterPro IPR010269 Type VI secretion system TssC-like
377 488 Pfam PF18945 EvpB/VC_A0108, tail sheath gpW/gp25-like domain
377 488 InterPro IPR044032 TssC1, C-terminal
19 489 NCBIfam TIGR03355 type VI secretion system contractile sheath large subunit
19 489 InterPro IPR010269 Type VI secretion system TssC-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2366
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.867