Protein profile

PA2414

L-sorbosone dehydrogenase

Genome: NC_002516.2

Gene: PA2414 Structure source: AlphaFold UniProt Q9I167
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Amino acids 439
Annotations 0
Features 16
PDB binders 0
Druggability 0.617

Overview

Basic information about this protein and its source genome.

Accession
PA2414
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2414
Status
annotated
Amino acids
439
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
CytoplasmicMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.617
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
24 43 MobiDBLite mobidb-lite consensus disorder prediction
27 439 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 19 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
65 437 SUPERFAMILY SSF50952 Soluble quinoprotein glucose dehydrogenase
65 437 InterPro IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase
10 21 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 26 Phobius SIGNAL_PEPTIDE Signal peptide region
12 436 PANTHER PTHR19328 HEDGEHOG-INTERACTING PROTEIN
1 24 SignalP_EUK SignalP-noTM SignalP-noTM
22 26 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 9 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 27 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
65 435 Gene3D G3DSA:2.120.10.30 -
65 435 InterPro IPR011042 Six-bladed beta-propeller, TolB-like
172 361 Pfam PF07995 Glucose / Sorbosone dehydrogenase
172 361 InterPro IPR012938 Glucose/Sorbosone dehydrogenase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2414
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.617
2 0.265