Protein profile

PA2458

hypothetical protein

Genome: NC_002516.2

Gene: PA2458 Structure source: AlphaFold UniProt Q9I124
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Amino acids 373
Annotations 0
Features 27
PDB binders 0
Druggability 0.421

Overview

Basic information about this protein and its source genome.

Accession
PA2458
Assembly
Pseudomonas aeruginosa PAO1, complete genome
Gene
PA2458
Status
annotated
Amino acids
373
Structure source
AlphaFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Gut microbiome off-target
hit
Essential (DEG)
N
Localization
OuterMembrane

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.421
Structure –
Pocket –

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

27 records
Show feature table
Start End DB Term Name
205 275 PANTHER PTHR32305 -
2 155 Gene3D G3DSA:2.180.10.10 -
156 370 Gene3D G3DSA:2.180.10.10 -
246 281 NCBIfam TIGR01643 YD repeat (two copies)
246 281 InterPro IPR006530 YD repeat
9 48 NCBIfam TIGR01643 YD repeat (two copies)
9 48 InterPro IPR006530 YD repeat
204 245 NCBIfam TIGR01643 YD repeat (two copies)
204 245 InterPro IPR006530 YD repeat
162 202 NCBIfam TIGR01643 YD repeat (two copies)
162 202 InterPro IPR006530 YD repeat
60 88 NCBIfam TIGR01643 YD repeat (two copies)
60 88 InterPro IPR006530 YD repeat
9 47 Pfam PF05593 RHS Repeat
9 47 InterPro IPR031325 RHS repeat
317 359 Pfam PF05593 RHS Repeat
317 359 InterPro IPR031325 RHS repeat
56 88 Pfam PF05593 RHS Repeat
56 88 InterPro IPR031325 RHS repeat
183 220 Pfam PF05593 RHS Repeat
183 220 InterPro IPR031325 RHS repeat
246 279 Pfam PF05593 RHS Repeat
246 279 InterPro IPR031325 RHS repeat
141 174 Pfam PF05593 RHS Repeat
141 174 InterPro IPR031325 RHS repeat
204 240 Pfam PF05593 RHS Repeat
204 240 InterPro IPR031325 RHS repeat

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold PA2458
AlphaFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.421
3 0.322