Protein profile

PA2530

hypothetical protein

Genome: NC_002516.2

Gene: PA2530 Structure source: AlphaFold UniProt Q9I0V3

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Amino acids 441

Annotations 2

Features 5

PDB binders 0

Druggability 0.731

Overview

Basic information about this protein and its source genome.

Accession: PA2530
Assembly: Pseudomonas aeruginosa PAO1, complete genome
Gene: PA2530
Status: annotated
Amino acids: 441
Structure source: AlphaFold

GO:0008237 Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0006508 The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

Target profile

Computed evidence for target prioritization.

Human off-target: No hit
Gut microbiome off-target: hit
Essential (DEG): N
Localization: Unknown

Selected Druggability evidence

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.731

Structure –

Pocket –

Sequence

Primary amino-acid sequence viewer.

MHQRQHFEALAEDLRRHLAEGEDFTLWYSAEDSEFIRFNRARVRQAGRVRQASALLRLIRDERQASLDLTLSGAPEEDRQRLAEGLRQLRQSLAWIPADPYLLLDTSAWQRENQDLGAAPDSGALLASLERRARDLDLVGIYAAGPLFRGFANSWGAFGWHAGSSFNFDWSLFHGNGQAVKADYAGQRWDDEAFARRFEQAREQLGHLGKPLRQLRPGDYRAYLAPAALEEVMQMLCWGGFSARALATGESPLQRLQNGDALLSPLLNLAERPATSPSPAFSAEGSPRAEVELVGNGRLSGRLVSSRSAREYGLVANGAGANEAPTALDMAGGSLEQARILEALDTGLYIGNLWYLNYSDMPAARLTGMTRFATFWVENGQIRAPVSTMRFDDSLYSFLGAHLEDLSHERELRLSSNTYGERQTDSMHLPGALTGRFTLTL

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

GO:0008237 Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
GO:0006508 The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

Sequence Features

Domain/signature hits from InterPro and related databases.

5 records

Show feature table

Start	End	DB	Term	Name
1	441	PANTHER	PTHR43666	TLDD PROTEIN
217	437	Pfam	PF19289	PmbA/TldA metallopeptidase C-terminal domain
217	437	InterPro	IPR045569	Metalloprotease TldD/E, C-terminal domain
1	440	SUPERFAMILY	SSF111283	Putative modulator of DNA gyrase, PmbA/TldD
1	440	InterPro	IPR036059	Metalloprotease TldD/PmbA superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

Loading 3D structure...

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry	Method	Resolution	Chain	Coverage	Links	Status
AlphaFold PA2530	AlphaFold	—	—	full sequence	—	Viewing

Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET	Sticks	Spheres	Surfaces	Druggability	Labels	Zoom	Positions
1				0.731